Standard type 1 DCs (cDC1s) excel at cross-presentation?of dead cell-associated antigens partly because they communicate DNGR-1, a receptor that recognizes revealed actin filaments on dead cells. reagents bound to polymerized F-actin with related effectiveness, the dimeric ECD bound more efficiently to F-actin in cell components (Number 1A). This observation suggested that the cellular ligand for… Continue reading Standard type 1 DCs (cDC1s) excel at cross-presentation?of dead cell-associated antigens