Polyadenylation of nascent RNA by poly(A) polymerase (PAP) is very important to 3 end maturation of virtually all eukaryotic mRNAs. polyadenylation (CPA) for 3 end maturation (1,2). After cleavage from the RNA polymerase II-bound nascent RNA, the RNA is usually polyadenylated to 250 nt in mammalian cells and 50 nt in candida (3). The poly(A)… Continue reading Polyadenylation of nascent RNA by poly(A) polymerase (PAP) is very important