History and Purpose Wearing-off is among the most frequent complications experienced by levodopa-treated individuals. [7]. To totally understand the effect of COMT-inhibition on cortical engine areas in PD individuals with WO, we likened practical magnetic resonance imaging (condition, Hoehn and Yahr level 2, MMSE rating 24, WO trend, levodopa treatment. PD, levodopa intake induces a… Continue reading History and Purpose Wearing-off is among the most frequent complications experienced