parasites lacking plasmepsin 4 (PM4), an aspartic protease that functions in the lysosomal compartment and contributes to hemoglobin digestion, have only a modest decrease in the asexual blood-stage growth rate; however, PM4 deficiency in the rodent malaria parasite results in significantly less virulence than that for the parental parasite. cerebral complications and, moreover, are able… Continue reading parasites lacking plasmepsin 4 (PM4), an aspartic protease that functions in