Background The activation of the immune system in neurodegeneration has detrimental as well as beneficial effects. peripheral nerve injury triggers an anti-inflammatory and immunosuppressive response, rather than a pro-inflammatory response. This was reflected by the complete absence of classical macrophage markers (iNOS, IFN, and IL12p40), and the strong up-regulation of tissue repair markers (arginase-1, Ym1,… Continue reading Background The activation of the immune system in neurodegeneration has detrimental