The mitochondrial tyrosyl-tRNA synthetases (mtTyrRSs) of Pezizomycotina fungi, a subphylum which includes many pathogenic species, are bifunctional proteins that both charge mitochondrial tRNATyr and become splicing cofactors for autocatalytic group I introns. with variants in essential intron binding areas, specially the Pezizomycotina-specific insertions. These insertions, which arose by growth of versatile termini or inner loops,… Continue reading The mitochondrial tyrosyl-tRNA synthetases (mtTyrRSs) of Pezizomycotina fungi, a subphylum which