Supplementary MaterialsSupplementary information dmm-11-033506-s1. major reason behind cisplatin-induced infertility. RNA sequencing data reveal that cisplatin causes a systemic tension response, where DAF-16/FOXO and SKN-1/NRF2, two conserved transcription elements, are fundamental regulators. We established that inhibition from the DNA damage-induced apoptotic pathway will not confer cisplatin safety to the pet. Nevertheless, mutants for the pro-apoptotic BH3-just… Continue reading Supplementary MaterialsSupplementary information dmm-11-033506-s1. major reason behind cisplatin-induced infertility. RNA sequencing