Background Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. By the age of 40, a male patient with CHM will typically have a significantly limited peripheral visual field, usually at the level of Bortezomib kinase… Continue reading Background Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations