The risk model was proposed by Polly Matzinger as complement to the traditional self-non-self- (SNS-) model to explain the immunoreactivity. lupus erythematous, rheumatoid arthritis, spondyloarthritis including ankylosing spondylitis, psoriasis, and Crohn’s disease and provide realistic approaches based on the logic of the danger model. We suppose that tissular dysfunction is certainly a prerequisite for chronic… Continue reading The risk model was proposed by Polly Matzinger as complement to